Biographical Sketch

  • In 2017,  Dr. Plamen Denchev started Tissue Culture Solutions,  a consulting business with one major goal in his mind - to help customers utilizing in vitro technologies for mass propagation of plants to set up, optimize, scale-up and commercialize their processes. 
  • In 2012,  Dr. Plamen Denchev joined Provitro Biosciences  as a Senior scientist. His accomplishments include: Optimized and consolidated research protocols into a base-line process for production of variety of plant species; Developed a scale up technology utilizing liquid medium and bioreactors for mass-production of plant species; Developed process maps and process control key parameters; Developed and optimized production Standard Operating Procedures (SOP); Optimized and established media formulation database and batch record system; Increased in vitro multiplication rates of various species by optimizing and modifying tissue culture media and micro-environmental conditions; Developed a database for capturing process efficiency and productivity in numerous plant species being produced in the facility
  • In 2004,  Dr. Plamen Denchev joined CellFor, Inc. as a Senior Research Manager. He was responsible for developing a commercial process for conifer trees production via somatic embryogenesis. He developed a strategy for new germplasm validation. He  established and proactively managed a research group for new line screening. Dr. Plamen Denchev developed, implemented and proactively managed a pilot group for protocol validation and system performances. He was responsible for large scale process and automation systems design, development and validation to support a 200 million seedling production program. Dr. Plamen Denchev directed a research team  to yield a range of new process step protocol improvements, media formulations and quality controlling. He was accountable for increasing marketing ability of CellFor by implementing new commercial pine lines to manufacturing as a result of screening and protocol development of new elite germplasm and commercial cryo bank. Dr. Plamen Denchev developed a  procedure for long term storage of desiccated mature somatic embryos. He established and coordinated research projects with academic institutions and the federal government. Dr.  Plamen Denchev planed and supervised pilot production of millions of mature somatic embryos and somatic seedlings for clients in Canada, Brazil, and the USA.
  • In 1996 Dr. Plamen Denchev joined Pacific Biotechnology, Inc. as a Senior Research Scientist. While with the company he was involved in setting up Pacific Biotechnology Inc. laboratory facility and responsible for designing and leading research programs for development of procedures for mass clonal propagation of conifer species via somatic embryogenesis.
  • In 1992,  Dr. Plamen Denchev started a postdoctoral research at the University of Tennessee, Knoxville directed on somatic embryogenesis in grasses. He developed a robust in vitro multiplication system for Switchgrass (Panicum virgatum L.) for bio fuel production.
  • In 1981, Dr. Plamen Denchev worked as a Senior Research Scientist at the Institute of Genetic Engineering, Bulgaria. His achievements include: Developed a procedure for direct somatic embryogenesis for dicot species including alfalfa, tomatoes, sunflower and sugar beet. Improved and optimized process for development and maturation of somatic embryos in flasks, airlift vessels and bio-reactors. Designed and organized laboratory units. Directly supervised PhD students and post doctoral fellows.
  • Throughout his carrier Dr. Plamen Denchev held consulting positions relating to establishment of new laboratory units, selecting and training personnel at universities, companies and other institutions involved in agriculture, horticulture and forestry. Dr. Plamen Denchev taught Plant Biotechnology courses at the University of Agriculture, Bulgaria.
  • Dr. Plamen Denchev holds 10 US patents and has authored or co-authored a number of scientific publications. He has been invited to give presentations about somatic embryogenesis and plant propagation in vitro at numerous national and international meetings. 
  • Dr. Plamen Denchev received his B.S. degree from the State University of Agriculture in Bulgaria and his Doctorate in Cell Genetics and Cell Biology from the Institute of Genetics, Moscow, Russia. He conducted postdoctoral research at the University of Tennessee, Knoxville, USA.

  • In 2017,  Dr. Plamen Denchev started Tissue Culture Solutions,  a consulting business with one major goal in his mind - to help customers utilizing in vitro technologies for mass propagation of plants to set up, optimize, scale-up and commercialize their processes. 
  • In 2012,  Dr. Plamen Denchev joined Provitro Biosciences  as a Senior scientist. His accomplishments include: Optimized and consolidated research protocols into a base-line process for production of variety of plant species; Developed a scale up technology utilizing liquid medium and bioreactors for mass-production of plant species; Developed process maps and process control key parameters; Developed and optimized production Standard Operating Procedures (SOP); Optimized and established media formulation database and batch record system; Increased in vitro multiplication rates of various species by optimizing and modifying tissue culture media and micro-environmental conditions; Developed a database for capturing process efficiency and productivity in numerous plant species being produced in the facility
  • In 2004,  Dr. Plamen Denchev joined CellFor, Inc. as a Senior Research Manager. He was responsible for developing a commercial process for conifer trees production via somatic embryogenesis. He developed a strategy for new germplasm validation. He  established and proactively managed a research group for new line screening. Dr. Plamen Denchev developed, implemented and proactively managed a pilot group for protocol validation and system performances. He was responsible for large scale process and automation systems design, development and validation to support a 200 million seedling production program. Dr. Plamen Denchev directed a research team  to yield a range of new process step protocol improvements, media formulations and quality controlling. He was accountable for increasing marketing ability of CellFor by implementing new commercial pine lines to manufacturing as a result of screening and protocol development of new elite germplasm and commercial cryo bank. Dr. Plamen Denchev developed a  procedure for long term storage of desiccated mature somatic embryos. He established and coordinated research projects with academic institutions and the federal government. Dr.  Plamen Denchev planed and supervised pilot production of millions of mature somatic embryos and somatic seedlings for clients in Canada, Brazil, and the USA.
  • In 1996 Dr. Plamen Denchev joined Pacific Biotechnology, Inc. as a Senior Research Scientist. While with the company he was involved in setting up Pacific Biotechnology Inc. laboratory facility and responsible for designing and leading research programs for development of procedures for mass clonal propagation of conifer species via somatic embryogenesis.
  • In 1992,  Dr. Plamen Denchev started a postdoctoral research at the University of Tennessee, Knoxville directed on somatic embryogenesis in grasses. He developed a robust in vitro multiplication system for Switchgrass (Panicum virgatum L.) for bio fuel production.
  • In 1981, Dr. Plamen Denchev worked as a Senior Research Scientist at the Institute of Genetic Engineering, Bulgaria. His achievements include: Developed a procedure for direct somatic embryogenesis for dicot species including alfalfa, tomatoes, sunflower and sugar beet. Improved and optimized process for development and maturation of somatic embryos in flasks, airlift vessels and bio-reactors. Designed and organized laboratory units. Directly supervised PhD students and post doctoral fellows.
  • Throughout his carrier Dr. Plamen Denchev held consulting positions relating to establishment of new laboratory units, selecting and training personnel at universities, companies and other institutions involved in agriculture, horticulture and forestry. Dr. Plamen Denchev taught Plant Biotechnology courses at the University of Agriculture, Bulgaria.
  • Dr. Plamen Denchev holds 10 US patents and has authored or co-authored a number of scientific publications. He has been invited to give presentations about somatic embryogenesis and plant propagation in vitro at numerous national and international meetings. 
  • Dr. Plamen Denchev received his B.S. degree from the State University of Agriculture in Bulgaria and his Doctorate in Cell Genetics and Cell Biology from the Institute of Genetics, Moscow, Russia. He conducted postdoctoral research at the University of Tennessee, Knoxville, USA.